Home LiteratureArticle Details
PMID: 10057305 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S.

Linguistic features of noncoding DNA sequences.

Physical review letters ·Vol. 73 ·No. 23 ·1994-12-05 ·Pages 3169-72

Mantegna RN, Buldyrev SV, Goldberger AL, Havlin S, Peng CK, Simons M, Stanley HE

Abstract

We extend the Zipf approach to analyzing linguistic texts to the statistical study of DNA base pair sequences and find that the noncoding regions are more similar to natural languages than the coding regions. We also adapt the Shannon approach to quantifying the "redundancy" of a linguistic text in terms of a measurable entropy function, and demonstrate that noncoding regions in eukaryotes display a smaller entropy and larger redundancy than coding regions, supporting the possibility that noncoding regions of DNA may carry biological information.

MeSH Terms
Algorithms Animals Base Sequence Codon, Nonsense DNA, Bacterial DNA, Fungal DNA, Helminth DNA, Viral Eukaryotic Cells Genetic Code Humans Language Linguistics Sequence Analysis, DNA Statistics as Topic
Chemicals
Codon, Nonsense DNA, Bacterial DNA, Fungal DNA, Helminth DNA, Viral
Authors & Affiliations
7 authors, click to expand affiliations / ORCID
Mantegna R N
Center for Polymer Studies and Department of Physics, Boston University, Massachusetts 02215, USA.
Buldyrev S V
Goldberger A L
Havlin S
Peng C K
Simons M
Stanley H E
Article Info
Journal
Physical review letters
Abbr.
Phys Rev Lett
ISSN
0031-9007
Published
1994-12-05
Pages
3169-72
Language
English
Region
United States
NLM ID
0401141
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: product@genelibs.com