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PMID: 1002136 Published · ppublish English Case Reports Journal Article

Localization of factors controlling spermatogenesis in the nonfluorescent portion of the human Y chromosome long arm.

Human genetics ·Vol. 34 ·No. 2 ·1976-10-28 ·Pages 119-24

Tiepolo L, Zuffardi O

Abstract

A deletion of the Y chromosome at the distal portion of band q11 was found in 6 men with normal male habitus but with azoospermia. Five of them were found during a survey of 1170 subfertile males while the sixth was karyotyped because of slight bone abnormalities. These findings, together with a review of the literature, suggest that on the distal portion of the nonfluoresecent segment of the long arm of the Y, factors are located controlling spermatogenesis.

MeSH Terms
Adult Chromosome Deletion Humans Infertility, Male/genetics Male Sex Chromosome Aberrations Sex Chromosomes Spermatogenesis
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Tiepolo L
Zuffardi O
References (26)
26 references, click to expand
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Article Info
Journal
Human genetics
Abbr.
Hum Genet
ISSN
0340-6717
DOI
10.1007/BF00278879
Published
1976-10-28
Pages
119-24
Language
English
Region
Germany
NLM ID
7613873
Subset
IM
External Links
PubMed source DOI: 10.1007/BF00278879 View journal details
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