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E-TABM-937 transcription profiling by array Homo sapiens

Transcription profiling by array of human multiple myeloma cells and cell lines; bone marrow stromal cells, bone marrow CD3 cells, bone marrow CD14 cells, bone marrow CD15 cells and in vitro generated osteoclastic cells from myeloma patients; and normal plasmablasts and normal memory B cells

提交 2010年3月5日 ·发布 2011年2月4日 ·更新 2014年5月2日

181

样本数

181

实验数

芯片平台

相关文献

实验描述

Multiple Myeloma primary myeloma cells of 131 patients, 10 human myeloma cell lines, bone marrow stromal cells of 5 myeloma patients, bone marrow CD3 cells of 5 myeloma patients, bone marrow CD14 cells of 5 myeloma patients, bone marrow CD15 cells of 5 myeloma patients, in vitro generated osteoclastic cells of 7 myeloma patients, 7 normal plasmablasts and 6 normal memory B cells.

参考文献

Cell Death via DR5, but not DR4, Is Regulated by p53 in Myeloma Cells

Sylvanie Surget,David Chiron,Patricia Gomez-Bougie,Géraldine Descamps,Emmanuelle Ménoret,Régis Bataille,Philippe Moreau,Steven Le Gouill,Martine Amiot,Catherine Pellat-Deceunynck

PMID: 22738917

Osteoclast-gene expression profiling reveals osteoclast-derived CCR2 chemokines promoting myeloma cell migration.

Moreaux J, Hose D, Kassambara A, Reme T, Moine P, Requirand G, Goldschmidt H, Klein B.

PMID: 21097672

Identification of pluripotent and adult stem cell genes unrelated to cell cycle and associated with poor prognosis in multiple myeloma.

Kassambara A, Hose D, Moreaux J, Rème T, Torrent J, Rossi JF, Goldschmidt H, Klein B.

PMID: 22860071

A high-risk signature for patients with multiple myeloma established from the molecular classification of human myeloma cell lines.

Moreaux J, Klein B, Bataille R, Descamps G, Maïga S, Hose D, Goldschmidt H, Jauch A, Rème T, Jourdan M, Amiot M, Pellat-Deceunynck C.

PMID: 21173094

ABT-737 is highly effective against molecular subgroups of multiple myeloma

Bodet L, Gomez-Bougie P, Touzeau C, Dousset C, Descamps G, Maïga S, Avet-Loiseau H, Bataille R, Moreau P, Le Gouill S, Pellat-Deceunynck C, Amiot M.

PMID: 21835956

Growth factors in multiple myeloma: a comprehensive analysis of their expression in tumor cells and bone marrow environment using Affymetrix microarrays.

Mahtouk K, Moreaux J, Hose D, Rème T, Meissner T, Jourdan M, Rossi JF, Pals ST, Goldschmidt H, Klein B.

PMID: 20465808

Gene expression-based prediction of myeloma cell sensitivity to histone deacetylase inhibitors.

Moreaux J, Reme T, Leonard W, Veyrune JL, Requirand G, Goldschmidt H, Hose D, Klein B.

PMID: 23868005

Development of Gene Expression-Based Score to Predict Sensitivity of Multiple Myeloma Cells to DNA Methylation Inhibitors

Jerome Moreaux; Thierry Reme; Wim Leonard; Jean-Luc Veyrune; Guilhem Requirand; Hartmut Goldschmidt; Dirk Hose; Bernard Klein

PMID: 23087257

芯片平台

A-AFFY-44

Affymetrix GeneChip Human Genome U133 Plus 2.0 [HG-U133_Plus_2]（181 例）

样本属性

CellLine

L363, LP1, OPM2, RPMI8226, SKMM2, U266, XG-1, XG-2, XG-3, XG-4

CellType

Bone marrow CD14 cells of myeloma patient, Bone marrow CD15 cells of myeloma patient, Bone marrow CD3 cells of myeloma patient, Bone marrow stromal cells of myeloma patient, bone marrow stromal cells of myeloma patient, In vitro generated osteoclasts of myeloma patient, In vitro generated Plasmablasts, memory B cells, myeloma cell

DiseaseState

multiple myeloma, normal

Organism

Homo sapiens

OrganismPart

bone marrow

实验信息

登记号

E-TABM-937

实验类型

transcription profiling by array

物种

Homo sapiens

提交日期

2010年3月5日

发布日期

2011年2月4日

更新日期

2014年5月2日

提交者

Jerome Moreaux

外部链接

ArrayExpress 原始页

分析服务

Transcription profiling by array of human multiple myeloma cells and cell lines; bone marrow stromal cells, bone marrow CD3 cells, bone marrow CD14 cells, bone marrow CD15 cells and in vitro generated osteoclastic cells from myeloma patients; and normal plasmablasts and normal memory B cells

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