Transcription profiling by array of rat ASNEOpancreas tumor cell line transplanted into a rat and the primary tumor and lymph node metastases profiled
ID:
状态:
发布时间Aug. 18, 2011
, 更新时间 June 10, 2011
, 提交时间 Aug. 18, 2010,
物种:
Rattus norvegicus
摘要:
Target of this study is to identify genes which are responsible for lymph node metastasis or primary pancreatic tumors. 1ASNEO is a pancreas tumor cell line, derived from a tumor which does not (hardly) metastasize. 1ASNEO cells are implanted into rat to induce tumor growth in transplanted rat. Cells from the induced primary tumor as well as from lymph node metastases are excised cultivated and profiled. Aliquots of these tumor cell lines are implanted in a subsequent rounds into other animals, reisolated and also profiled