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题目:: shRNA profiling of human T-ALL cell lines - inhibition of TAL1 and NKX3.1 in T-ALL
ID:
状态:: 发布时间May 12, 2010 , 更新时间 June 10, 2011 , 提交时间 May 25, 2009,
物种:: Homo sapiens
摘要:: We decreased TAL1 and NKX3.1 proteins levels using lentiviral deliveries of shTAL1 and shNKX3.1 in TAL1 expressing human T-ALL cell lines. Growth curves of cell lines showed that reduced TAL1 and NKX3.1 expressions resulted in a first phase where the number of cells did not increase likewise the shCTL expressing cells. To identify TAL1 and NKX3.1 target genes involved in T-ALL cell growth, we performed gene expression profiling of cell lines expressing shTAL1, shNKX3.1 or shCTL after two and three days of culture.
实验种类:: RNAi profiling by array
样本量:: 6
实验设计:
: 无设计数据
数据号:: E-MEXP-2197
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