| GeneLibs

题目:: Transcription profiling of Ayshba gossypii wild type and transcription factor AgTec1 and AgSte12 and repressor AgDig1.2 deletion mutant strains
ID:
状态:: 发布时间Jan. 31, 2011 , 更新时间 May 2, 2014 , 提交时间 Jan. 12, 2009,
物种:: Ashbya gossypii
摘要:: The goal of this experiment concerned the comparison of genes controling the mating and filamentation pathways in S. cerevisiae and the filamentous fungus A. gossypii. Even though the A. gossypii genome encodes homologous genes of all components of these two pathways, there are major differences in the modes of growth beween the two organisms, and the potential for mating is unknown in A. gossypii. To shed light on functional conservation the two pathway including transcriptional regulation, a bioinfomatics analysis that looked into transcription factor conservation was carried out. To experimentally investigate regulatory network conservation, the two transcription factors AgTec1. AgSte12 and the repressor AgDig1.2 that act at the end of the pathways were deleted. Subsequent comparisons of mRNA levels of the deletion mutants with wild type allowed the identification of genes and gene groups which are regulated by the transcription factors or the repressor.
实验种类:: transcription profiling by array
样本量:: 10
实验设计:
: 无设计数据
数据号:: E-MEXP-1954
数据状态:: 无法自动分析，您可以尝试手动分析数据。

实验库数据相关信息