Transcription profiling of equine fibroblasts transformed with Bovine Paillomarvirus type1 experimentally or from explanted sarcoids compared to control fibroblasts
ID:
状态:
发布时间July 12, 2008
, 更新时间 May 2, 2014
, 提交时间 June 18, 2008,
物种:
Equus caballus
摘要:
Bovine Papillomavirus type 1 (BPV-1) and less commonly BPV-2 are associated with the pathogenesis of common equine skin tumours termed sarcoids. In an attempt to understand the mechanisms by which BPV-1 induces sarcoids, we used gene expression profiling as a screening tool to identify candidates genes implicated in disease pathogenesis. Gene expression profiles of equine fibroblasts transformed by BPV-1 either experimentally or from explanted tumours were compared with control equine fibroblasts to identify genes associated with expression of BPV-1.