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E-MEXP-1649 transcription profiling by array Mus musculus

Transcription profiling of mouse liver cells with liver specific deletion of Irs1 and/or Irs2 and Foxo1during fasting and feeding

提交 June 11, 2008 ·发布 July 31, 2008 ·更新 May 2, 2014

样本数

实验数

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相关文献

实验描述

The effect of liver specific deletion of the insulin receptor substrate-1 (Irs1) and/or Irs2 upon gene expression in the fasted and fed liver of mice; and the effect of liver specific Foxo1 deletion in the Irs1 and Irs2 knockout liver during fasting and feeding.

参考文献

IRS1-BRANCH OF THE INSULIN SIGNALING CASCADE PLAYS A DOMINANT ROLE IN HEPATIC NUTRIENT HOMEOSTASIS

Guo, Shaodong; Copps, Kyle D.; Dong, Charlie; Park, Sunmin; Cheng, Zhiyong; Pocai, Alessandro; Rossetti, Luciano; Sajan, Mini; Farese, Robert V.; White, Morris F.

芯片平台

A-AFFY-45

Affymetrix GeneChip Mouse Genome 430 2.0 [Mouse430_2]（32 例）

样本属性

Age

6 weeks

BioSourceType

fresh_sample

DevelopmentalStage

adult

GeneticModification

gene_knock_out

Genotype

Irs1 L/L, Irs1 L/L::Irs2 L/L, Irs1 L/L::Irs2 L/L::Foxo1 L/L, Irs2 L/L, Liver Specific Irs1 -/-, Liver Specific Irs1 -/-::Irs2 -/-, Liver Specific Irs1 -/-::Irs2 -/-::Foxo1 -/-, Liver Specific Irs2 -/-

Organism

Mus musculus

OrganismPart

liver

provider

Children's Hospital Boston

Sex

male

StrainOrLine

c57Bl6::129

TargetedCellType

hepatocyte

实验信息

登记号

E-MEXP-1649

实验类型

transcription profiling by array

物种

Mus musculus

提交日期

June 11, 2008

发布日期

July 31, 2008

更新日期

May 2, 2014

提交者

Morris F White

外部链接

ArrayExpress 原始页

分析服务

Transcription profiling of mouse liver cells with liver specific deletion of Irs1 and/or Irs2 and Foxo1during fasting and feeding

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