Transcription profiling of mouse dermal fibroblasts upon UV irradiation in a time-, dose- and lesion-dependent manner
ID:
状态:
发布时间Sept. 1, 2004
, 更新时间 May 2, 2014
, 提交时间 June 3, 2004,
物种:
Mus musculus
摘要:
Each labeled cDNA sample constituted a unique combination of UV dose (2J, 4J or 8J), time point (-30min, 0h, 2h, 4h, 8h and 24h) and photoreactivation status (PR or non-PR) that defined a distinctive matrix point. All samples were hybridized to non-irradiated, non-photoreactivated MDFs of the pertinent time point. As a consequence, the net observed differences in gene expression profiles between treated and non-treated cells depicted only the time-dependent expression profiles of significant gene entries upon a 2J, 4J or 8J of UV-C irradiation and subsequent photoreactivation or not.