| GeneLibs

题目:: Transcription profiling of human neutrophil and PBMC gene expression data from Jobs Syndrome individuals
ID:
状态:: 发布时间June 17, 2008 , 更新时间 May 2, 2014 , 提交时间 July 17, 2007,
物种:: Homo sapiens
摘要:: Hyper IgE Recurrent Infection Syndrome (HIES or Job’s syndrome), is a rare disorder of immunity and connective tissue, typically manifest with boils, cyst-forming pneumonias, and extremely elevated serum IgE as well as retained primary dentition and bone abnormalities. Inheritance can be autosomal dominant. In order to identify a specific defect or gene of interest, we performed microarray expression analysis on samples from patients with Job's syndrome and from healthy control subjects. Experiment Overall Design: Polymorphonuclear leukocytes (PMNs) and peripheral blood mononuclear cells (PBMCs) were isolated from whole blood from patients with Job's syndrome and healthy control subjects. PMNs and PBMCs were incubated with or without IgG- and C3bi-coated latex beads for 3 and 6 hours.
实验种类:: transcription profiling by array
样本量:: 141
实验设计:
: 无设计数据
数据号:: E-GEOD-8507, GSE8507
数据状态:: 无法自动分析，您可以尝试手动分析数据。

实验库数据相关信息