Molecular landscape of modified histones in Drosophila heterochromatin
ID:
状态:
发布时间June 29, 2010
, 更新时间 May 2, 2014
, 提交时间 May 17, 2007,
物种:
Drosophila melanogaster
摘要:
The aim of this study is to analyze the distribution of the modified histones in and around peri-centromeric heterochromatin at high resolutions for understanding the molecular nature of the heterochromatic genes and euchromatin-heterochromatin transition. Since heterochromatin is repeat-rich, stringent repeat-filtering was applied in the genome-tiling array design. When possible, parallel analyses were performed with two different types of reference controls, namely total genomic DNA and histone H3 C-terminus ChIP.