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题目:: Transcription profiling of primary human keratinocytes
ID:
状态:: 发布时间June 14, 2008 , 更新时间 March 27, 2012 , 提交时间 Dec. 18, 2006,
物种:: Homo sapiens
摘要:: Oncogenic Ras induces epidermal cell growth arrest. Induction of the JNK/Ap1 signaling cascade by expression of MKK7 overcomes Ras-induced cell growth arrest in a manner dependent on AP1 fucntion. We used microarrays to detail the global programme of gene expression in response to MKK7, Ras activation and AP1 inhibition Experiment Overall Design: To study the gene expression profile responsive to Ras and MKK7 expression. We used retroviral expression system to express LacZ, MKK7, Ras, DNc-Jun, MKK7+Ras, and MKK7+Ras +DNc-Jun in primary human keratinocytes, and then extract total RNA from the transduced cells for gene expression analysis.
实验种类:: transcription profiling by array
样本量:: 6
实验设计:
: 无设计数据
数据号:: E-GEOD-6559, GSE6559
数据状态:: 无法自动分析，您可以尝试手动分析数据。

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