实验库 数据相关信息

题目:
Transcription profiling of human A549 NSCLC cells cisplatin induced changes
ID:
状态:
发布时间June 14, 2008 , 更新时间 March 27, 2012 , 提交时间 Dec. 1, 2006,
物种:
Homo sapiens
摘要:
Affymetrix high-density oligonucleotide microarray analysis was performed to analyse cisplatin-induced gene expression changes in A549 NSCLC cells. Cells were treated with 50 µM of cisplatin for 1 hour and incubated for a further 10 hours in drug-free media before the gene expression changes were investigated. Results show that cisplatin induced changes in the expression of genes involved in apoptosis, cell cycle control, DNA repair and transcription. Experiment Overall Design: Gene expression changes in response to cisplatin were analysed by Microarray technology in A549 NSCLC cells. Cells were treated with 50 µM of cisplatin (or drug-free media) for 1 hour and incubated for a further 10 hours in drug-free media before the cisplatin-induced gene expression changes were investigated. Control and cisplatin-treated samples were collected from three independent experiments.
实验种类:
transcription profiling by array
样本量:
6
实验设计:
无设计数据
数据号:
E-GEOD-6410, GSE6410
数据状态:

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