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题目:: The global transcriptional profile of Mycobacterium tuberculosis during human macrophages infection
ID:
状态:: 发布时间May 27, 2010 , 更新时间 May 2, 2014 , 提交时间 Nov. 1, 2006,
物种:: Mycobacterium tuberculosis
摘要:: During lung infection Mycobacterium tuberculosis (Mtb) resides in macrophages and subverts the bactericidal mechanisms of these professional phagocytes. In this work we have analyzed by DNA microarray technique the global transcription profile of Mtb infecting primary human macrophages in order to identify putative bacterial pathogenic factors that can be relevant for the intracellular survival of Mtb. Keywords: time course We compared the global gene expression of the H37Rv strain of Mtb after 4 hours and 24 hours of infection of human macrophage-like THP-1 cells with the gene expression profile of the strain growing exponentially in broth cultures.
实验种类:: transcription profiling by array
样本量:: 22
实验设计:
: 无设计数据
数据号:: E-GEOD-6209, GSE6209
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