实验描述
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
参考文献
PIK3CA(H1047R) induces multipotency and multi-lineage mammary tumours
Koren S, Reavie L, do Couto JP, De Silva D, Stadler MB, Roloff T, Britschgi A, Eichlisberger T, Kohler H, Aina O, Cardiff RD, Bentires-Alj M
PMID: 26266975
芯片平台
A-AFFY-130
Affymetrix GeneChip Mouse Gene 1.0 ST Array [MoGene-1_0-st-v1](49 例)
样本属性
animal
Lgr5-creERT2 control mice, Lgr5-creERT2/PIK3CA H1047R mice
cell type mammary cell subpopulation
basal subset H1047R-expressing, basal subset Lgr5-expressing, basal subset without Lgr5 and H1047R-expression, basal subset without Lgr5-expression, luminal subset CD24high Sca1 negative, luminal subset CD24high Sca1 negative H1047R-expressing, luminal subset CD24high Sca1 positive, luminal subset CD24high Sca1 positive H1047R-expressing
genotype
K8-creERT2 ctrl, K8-creERT2/PIK3CA H1047R, Lgr5-creERT2 ctrl, Lgr5-creERT2/PIK3CA H1047R
organism part
mammary gland, mammary tumor, preneoplastic mammary gland
strain
mixed background FVB/C57/BL6, mixed background FVB/C57BL6, mixed background FVB/CD1