实验描述
This study examined the gene expression profile of mammary tumors derived from Lgr5- and K8-positive cell-of-origins Mammary tumors and reference mammary glands from control mice were collected, cryo-homogenized, total RNA was isolated and analyzed by microarray (total 25 samples).
参考文献
PIK3CA(H1047R) induces multipotency and multi-lineage mammary tumours
Koren S, Reavie L, do Couto JP, De Silva D, Stadler MB, Roloff T, Britschgi A, Eichlisberger T, Kohler H, Aina O, Cardiff RD, Bentires-Alj M
PMID: 26266975
芯片平台
A-AFFY-130
Affymetrix GeneChip Mouse Gene 1.0 ST Array [MoGene-1_0-st-v1](25 例)
样本属性
genotype
K8-creERT2 ctrl, K8-creERT2/PIK3CA H1047R, Lgr5-creERT2 ctrl, Lgr5-creERT2/PIK3CA H1047R
organism part
mammary gland, mammary tumor
strain
mixed background FVB/C57/BL6, mixed background FVB/CD1