Transcription profiling of mouse overexpressing MHC-I after endurance training
ID:
状态:
发布时间June 13, 2008
, 更新时间 March 27, 2012
, 提交时间 July 12, 2006,
物种:
Mus musculus
摘要:
Myosine heavy chain I was overexpressed in mouse skeletal muscle. The transgenic mice, as well as the wild type mice, were endurance trained on treadmill for 5 days/week over 8 weeks at 80% peak aerobic capacity in comparison with untrained mice. The gene expression profiles of the skeletal muscles from wild-type trained (WTT) and untrained (WTUT), and transgenic trained (TGT) and untrained (TGUT) were measured using Affymetrix Mouse430A 2.0 GeneChips. Experiment Overall Design: There were 5 WTT, 5 WTUT, 5 TGT, and 5 TGUT mice used in microarray studies.