Transcription profiling of difference in immune response to hantavirus by Rattus norvegicus male and female animals
ID:
状态:
发布时间Oct. 10, 2007
, 更新时间 June 10, 2011
, 提交时间 July 1, 2003,
物种:
Rattus norvegicus
摘要:
In the field, adult male rodents are more frequently infected with hantaviruses than females. Early data suggests that sex steroid hormones modulate sex differences in host immune response. This project focuses on elucidating sex differences in gene expression in the lungs of infected males 15 and 40 days post infection with Seoul virus (naturally occurring hantavirus in Norway rats) relative to infected females 15 and 40 days post infection on 12 RG_U34 GeneChips.