Transcription profiling of mouse allergen-induced goblet cells
ID:
状态:
发布时间June 13, 2008
, 更新时间 June 10, 2011
, 提交时间 June 27, 2003,
物种:
Mus musculus
摘要:
High numbers of goblet cells in airways contribute to the mucus obstruction characteristic of asthmatic airways. Allergen challenged mice exhibit robust expression of goblet cells within airway surface epithelium. This study looks at the temporal analysis of IL-13 exposed murine airways to elucidate pathways that result in differentiation of airway epithelial cells to goblet cells.