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题目:: PHA-4 organogenesis
ID:
状态:: 发布时间Nov. 25, 2005 , 更新时间 March 27, 2012 , 提交时间 Nov. 25, 2005,
物种:: Caenorhabditis elegans
摘要:: The pha-4 locus encodes a forkhead box A (FoxA/HNF3) transcription factor homolog that specifies organ identity for Caenorhabditis elegans pharyngeal cells. We used microarrays to identify pharyngeal genes and analyzed those genes to determine which were direct PHA-4 targets. Our data suggest that PHA-4 directly activates most or all pharyngeal genes. Furthermore, the relative affinity of PHA-4 for different TRTTKRY (R = A/G, K = T/G, Y = T/C) elements modulates the onset of gene expression, providing a mechanism to activate pharyngeal genes at different developmental stages. We suggest that direct transcriptional regulation of entire gene networks may be a common feature of organ identity genes. A genotyping experiment design type classifies an individual or group of individuals on the basis of alleles, haplotypes, SNP's. Computed
实验种类:: unknown experiment type
样本量:: 6
实验设计:
: 无设计数据
数据号:: E-GEOD-3681, GSE3681
数据状态:: 无法自动分析，您可以尝试手动分析数据。

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