| GeneLibs

题目:: Molecular characterization of immortalization of human MSCs by a combination of p53 knockdown and TERT overexpression
ID:
状态:: 发布时间April 13, 2011 , 更新时间 April 26, 2011
物种:: Homo sapiens
摘要:: Gene expression profile of p53 knockdown MSCs or p53 knockdown+TERT MSCs was compared with that of control MSCs. Our data show p53 knockdown prolongs the lifespan of MSCs, and a combination of p53 knockdown and TERT overexpression is sufficient to immortalize MSCs. The results provide important information about the molecular basis underlying p53 knockdown in MSCs and immortalization-related genes of MSCs. Total RNA obtained from p53 knockdown MSCs or p53 knockdown+TERT MSCs from three patients were compared with control MSCs.
实验种类:: transcription profiling by array
样本量:: 9
实验设计:
: 无设计数据
数据号:: E-GEOD-28546, GSE28546
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