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题目:: Gene expression profiles of mouse Blimp1 +/gfp and Blimp1 gfp/gfp regulatory T cells
ID:
状态:: 发布时间Feb. 9, 2011
物种:: Mus musculus
摘要:: Regulatory T (Treg) cells are required for peripheral tolerance. Recent evidence indicates that Treg cells can adopt specialized differentiation programs in the periphery that are controlled by transcription factors usually associated with T helper differentiation. We demonstrate that expression of the transcription factor Blimp1 defines a population of Treg cells that localize predominantly to mucosal sites and produces IL-10. Blimp1 is required for IL-10 production by these cells and for their tissue homeostasis. A list of differentially expressed genes were identified from this whole-genome expression profiling experiment. Mouse Blimp1 +/gfp and Blimp1 gfp/gfp regulatory T cells were analyzed. Three replicates each.
实验种类:: transcription profiling by array
样本量:: 6
实验设计:
: 无设计数据
数据号:: E-GEOD-27143, GSE27143
数据状态:: 无法自动分析，您可以尝试手动分析数据。

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