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题目:: Nociceptor differentiation from pluripotent cells
ID:
状态:: 发布时间April 1, 2011 , 更新时间 April 14, 2011
物种:: Homo sapiens
摘要:: Here we performed the first combinatorial small molecule screen for the rapid conversion of hPSCs into postmitotic neurons. We identified a combination of five small molecule pathway inhibitors sufficient to yield neurons at > 75% efficiency within 10 days of differentiation in the absence of any recombinant growth factors. The resulting human neurons express canonical markers of nociceptive sensory fate. Two treatments (LSB and 3i) at days 2,3,5,7,9, and 15, in triplicate
实验种类:: transcription profiling by array
样本量:: 33
实验设计:
: 无设计数据
数据号:: E-GEOD-26867, GSE26867
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