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题目:: Transcription profiling of cell lines produced from premalignant tumors with induced sensence
ID:
状态:: 发布时间Oct. 2, 2007 , 更新时间 March 27, 2012 , 提交时间 April 4, 2005,
物种:: Homo sapiens
摘要:: Oncogene-induced senescence is a cellular response that may be crucial for protection against cancer development, but its investigation has so far been restricted to cultured cells that have been manipulated to overexpress an oncogene. Here we analyse tumours initiated by an endogenous oncogene, ras, and show that senescent cells exist in premalignant tumours but not in malignant ones. Senescence is therefore a defining feature of premalignant tumours that could prove valuable in the diagnosis and prognosis of cancer.
实验种类:: transcription profiling by array
样本量:: 10
实验设计:
: 无设计数据
数据号:: E-GEOD-2487, GSE2487, GDS1637
数据状态:: 无法自动分析，您可以尝试手动分析数据。

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