| GeneLibs

题目:: Effect of imatinib on philadelphia chromosome positive acute lymphoblastic leukemia
ID:
状态:: 发布时间Sept. 10, 2010 , 更新时间 June 10, 2011
物种:: Homo sapiens
摘要:: The Philadelphia chromosome (Ph) encodes the oncogenic BCR-ABL1 tyrosine kinase, which defines a subset of acute lymphoblastic leukemia (ALL) with a particularly unfavorable prognosis. In this study, the tyrosine kinase inhibitor imatinib was used for pharmacological inhibition of BCR-ABL1. Gene expression profiles of Ph+ ALL cell lines were analyzed in response to imatinib treatment. Four Ph+ ALL cell lines (BV-173, NALM-1, SUP-B15, and TOM1) were either treated with 10µM STI571 (Imatinib) for 16 hours or cultured in absence of STI571.
实验种类:: transcription profiling by array
样本量:: 8
实验设计:
: 无设计数据
数据号:: E-GEOD-23743, GSE23743
数据状态:: 无法自动分析，您可以尝试手动分析数据。

实验库数据相关信息