Systemic transcriptome alternation under mtDNA depletion in 143B TK- osteosarcoma cells
ID:
状态:
发布时间July 17, 2010
, 更新时间 June 10, 2011
物种:
Homo sapiens
摘要:
The mitochondrial protein repertoire varies depending on cellular states, tissue type, species, and disease state. However, little is known about how this repertoire changes under different cellular or disease states. To gain a better understanding of dynamic mitochondrial proteomic changes, we compared alterations of mitochondrial proteome with transcriptome under mitochondrial DNA depletion. Total RNA obtained from 143B TK- osteosarcoma ρ+ cells or 143B TK- osteosarcoma ρ° cells