Identification of differentially methylated regions between placentas and maternal blood cells on chromosome 18
ID:
状态:
发布时间Dec. 22, 2010
, 更新时间 May 1, 2014
物种:
Homo sapiens
摘要:
Comparison of DNA methylation levels of chromosome 18 between placentas and blood cells of pregnant women Extracted DNA from 5 cases of placental tissues and 5 cases of maternal blood cell was subjected to MeDIP (methylated DNA immunoprecipitation) and hybridized to Affymetrix GeneChip® Human Tiling 2.0R Array sets. A control without immunoprecipitation (IP) was also processed in parallel with the immunoprecipitated DNA samples. The results were validated with bisulfite sequencing and mass spectrometry-based analysis