Mouse Models of Alveolar/Embryonal Rhabdomyosarcoma & Spindle Cell Sarcomas
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状态:
发布时间Feb. 17, 2011
, 更新时间 March 27, 2012
物种:
Mus musculus
摘要:
A series of conditional mouse models of embryonal rhabdomyosarcoma, alveolar rhabdomyosarcoma and spindle cell sarcoma were generated and validated for relavence to corresponding human cancers. Conditional mouse models of embryonal rhabdomyosarcoma, alveolar rhabdomyosarcoma and spindle cell sarcoma were created by activation or deletion of Pax3:Fkhr, p53, Ptch1 or Rb1 genes.