Time course study of experimental cardiac hypertrophy in rat
ID:
状态:
发布时间May 27, 2010
, 更新时间 May 1, 2014
, 提交时间 April 28, 2010,
物种:
Rattus norvegicus
摘要:
To further investigate the role of hyaluronan and the regulation of its synthesis in cardiac hypertrophy, quantitative measurements of myocardial hyaluronan was correlated to gene transcription in hypertrophic cardiac tissue. Factor analysis was used to study correlation over time. Abdominal aorta was ligated in Wistar rats. Heart was excised 1 day, 6 days and 42 days after operation. Aorta ligated animals was compared to sham operated animals. N=6 in each time group, except aorta ligated after six days where n=5.