An integrative multi-dimensional genetic and epigenetic strategy to identify aberrant genes and pathways in cancer: CGH
ID:
状态:
发布时间Dec. 31, 2010
, 更新时间 May 1, 2014
物种:
Homo sapiens
摘要:
This study was undertaken to identify novel tumour suppressor genes in lung adenocarcinoma. EYA4, located at 6q23.2 was identified as a frequently lost and hypermethylated gene in the analyzed samples. 7 Breast cancer cell lines profiled on the SMRTr array in conjunction with matched DNA methylation data, allelic status and gene expression data for integrative analysis.