MicroRNA expression profile in Dgcr8-homozygous mutant mouse embryonic stem cells
ID:
状态:
发布时间Sept. 1, 2010
, 更新时间 June 10, 2011
物种:
Mus musculus
摘要:
We investigated the effect of Dgcr8-homozygous mutation on microRNA expression profile in mouse embryonic stem cells. MicroRNA expression was substantially impaired, indicating a pivotal role of DGCR8 in microRNA biogenesis. MicroRNA expression profile was compared between Dgcr8-homozygous mutant ES cells and wild-type ES cells