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题目:: Expression data from white and brown adipose tissue (WAT and BAT) of per2-/- and control mice
ID:
状态:: 发布时间Oct. 19, 2010 , 更新时间 June 10, 2011 , 提交时间 Feb. 2, 2010,
物种:: Mus musculus
摘要:: We found that the circadian protein PER2 interacts with the nuclear receptor PPARgamma to repress its activity. PPARgamma is a master regulator of adipogenesis and lipid metabolism and is very abundant in adipose tissue. We used microarrays to detail the global program of gene expression in adipose tissue lacking the per2 gene. This analysis identified several PPARgamma target genes up-regulated in adipose tissue from per2-/- mice. Per2-/- and per2+/+ male mice (Bae et al., 2001) were housed under 12 hr light/12 hr dark (LD) cycles. Mice 20 weeks old were sacrificed at the same time and adipose tissue (WAT and BAT) was collected for RNA extraction. 3 biological replicates per mouse/tissue.
实验种类:: transcription profiling by array
样本量:: 12
实验设计:
: 无设计数据
数据号:: E-GEOD-20165, GSE20165
数据状态:: 无法自动分析，您可以尝试手动分析数据。

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