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题目:: Identification of Sfh and H-NS binding sites in the Salmonella Typhimurium genome
ID:
状态:: 发布时间May 18, 2010 , 更新时间 May 1, 2014 , 提交时间 Nov. 30, 2009,
物种:: Salmonella enterica subsp. enterica serovar Typhimurium
摘要:: The global regulator H-NS represses transcription in gram negative bacteria. Sfh is a homologue of H-NS and is encoded by plasmid pSfR27. Sfh provides a 'stealth' function that allows pSfR27 to be transmitted to a new host without disrupting the competitive fitness of the new host We used ChIP-on-chip to profile Sfh (3xFLAG-tagged) and H-NS binding sites in Salmonella Typhimurium strain SL1344 and found that Sfh provides its 'stealth' function by targeting a sub-set of H-NS bound genes that display reduced levels of H-NS occupancy with the SL1344 chromosome upon acquisition of plasmid pSfR27 Identification of Sfh binding sites in strains SL1344 (pSfR27) and SL1344 hns (pSfR27) as well as identification of H-NS binding sites in strains SL1344, SL1344 (pSfR27), and SL1344 (pSfR27) sfh
实验种类:: ChIP-chip by array
样本量:: 16
实验设计:
: 无设计数据
数据号:: E-GEOD-19231, GSE19231
数据状态:: 无法自动分析，您可以尝试手动分析数据。

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