Orthotopic Xenograft Model of Ependymoma that Maintains Genomic Signature of the Primary Tumor
ID:
状态:
发布时间Aug. 8, 2009
, 更新时间 May 1, 2014
, 提交时间 Aug. 4, 2009,
物种:
Homo sapiens
摘要:
The hypothesis was that the orthotopic xenograft model of ependymoma faithfully recapitulate the genomics signatures of the original tumor patient tissue Original tumor cells were implanted into the same location of SCID mice and check for transcriptome profiles upon subsequent passages to show that the passages preserve the overall genomics signature of the original tumor tissue.