Transcription profiling of human Downs syndrome with acute lymphoblastic pediatric leukemia (DS-ALL) patients
ID:
状态:
发布时间Jan. 15, 2010
, 更新时间 March 27, 2012
, 提交时间 July 31, 2009,
物种:
Homo sapiens
摘要:
DS-ALL is a highly heterogeneous disease with predominance of an aberrant exp. of CRLF2 cooperating with mutated JAK2; Acute lymphoblastic pediatric leukemia specimens of Down's syndrome are examined for gene expression profiles and specific genetic aberrations. Gene expression profiling and specific genetic variation analysis identify novel pathways involved in DS-ALL pathogenesis. Experiment Overall Design: Gene expression profile analysis and specific genetic data are integrated to find characteristics of DS-ALL's