Microarray analysis to identify the molecular mechanisms whereby pDCs confer growth and drug resistance in MM cells
ID:
状态:
发布时间July 31, 2009
, 更新时间 March 27, 2012
物种:
Homo sapiens
摘要:
Multiple Myeloma (MM) remains incurable despite novel therapies, suggesting the need for further identification of factors mediating tumorigenesis and drug resistance. We performed microarray analysis to identify the molecular mechanisms whereby pDCs confer growth and drug resistance in MM cells. Comparsion of MM cells in the presence and absence of pDCs (plasmacytoid dendritic cells)