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题目:: Analysis of alternative splicing in mouse tissues with differentiation, disease and development
ID:
状态:: 发布时间July 10, 2009 , 更新时间 June 10, 2011 , 提交时间 July 7, 2009,
物种:: Mus musculus
摘要:: Two major goals for regenerative medicine are to reproducibly transform adult somatic cells into a pluripotent state and to control their differentiation into specific cell fates. These goals could be furthered by obtaining a complete picture of the RNA isoforms produced by these cells due to alternative splicing (AS) and alternative promoter selection (APS). To investigate the roles of AS and APS, reciprocal exon-exon junctions were interrogated on a genome-wide scale in differentiating mouse embryonic stem cells (ESCs), mouse myometrium throughout gestation and cardiac remodeling with disease using a prototype Affymetrix microarray. Using a custom analysis package named AltAnalyze (
实验种类:: transcription profiling by array
样本量:: 57
实验设计:
: 无设计数据
数据号:: E-GEOD-17021, GSE17021
数据状态:: 无法自动分析，您可以尝试手动分析数据。

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