mRNA expression data from differentiation of human ESCs into definitive endoderm, Cyt49 on matrigel
ID:
状态:
发布时间July 30, 2010
, 更新时间 March 27, 2012
物种:
Homo sapiens
摘要:
hESCs can differentiate into the three primary embryonic lineages (endoderm, mesoderm, ectoderm) as well as extraembryonic tissues. Definitive endoderm (DE) is the first step into the pathway to endoderm derived tissues: pancreas, liver, gut, lung. We used microarrays to detail the changes in mRNA expression during the transition from pluripotent hESCs into definitive endoderm. hESCs (Cyt49) were differentiated in the presence of Activin A and Wnt3A under low serum conditions to induce DE formation. Samples were collected at day 0, day 2 and day 4.