Analysis of the microRNA that involved the tuberculosis or latent TB infection
ID:
状态:
发布时间May 19, 2010
, 更新时间 May 3, 2014
, 提交时间 May 5, 2009,
物种:
Homo sapiens
摘要:
To get to know the different levels of the microRNA among the pulmonary tuberculosis patients, latent-infected individuals and the complete healthy people, we have employed the Agilent miRNA microarray (version 2.0) as a discovery platform to identify microRNA with the potential to diagnose the TB patients and the latent infected persons. Each group have 4 volunteers. The Peripheral Blood Mononuclear Cells (PBMCs) of each group were made up of equally mixed volumes. The results showed that several microRNAs were found up- or low regulated in PBMCs of TB patients versus latent-infected individuals and similarly for latent-infected individuals versus complete healthy ones. Each group have 4 volunteers. The PBMCs of each group were made up of equally mixed volumes after being purified.