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题目:: Transcription profiling of human naive and HVC-replicon containing Huh7 cells were treated with CsA or NIM811 to investigate mode of action of these drugs and identified host factors essential for HCV replication in a subgenomic replicon model
ID:
状态:: 发布时间May 11, 2009 , 更新时间 June 10, 2011 , 提交时间 May 3, 2009,
物种:: Homo sapiens
摘要:: Cyclophilin binding drugs, NIM811 and cyclosporin A (CsA), inhibit the replication of HCV replicon. We investigated the mode of action of these drugs and identified host factors essential for HCV replication in a subgenomic replicon model. Experiment Overall Design: Cultured Huh7 cell were treated with CsA or NIM811 at different concentrations. Cells were harvested after 12, 24 or 48 hours. The extracted mRNA were hybridized on Affymetrix U133 Plus 2 microarrays.
实验种类:: transcription profiling by array
样本量:: 82
实验设计:
: 无设计数据
数据号:: E-GEOD-15935, GSE15935
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