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题目:: Loss of tight junction integrity induces loss of epithelial phenotype: case of Claudin11 knock out in testis
ID:
状态:: 发布时间April 11, 2010 , 更新时间 May 1, 2014
物种:: Mus musculus
摘要:: Epithelium barrier integrity is assumed at least in part by the presence of junctions between cells. Tight-junction formation may be necessary for Sertoli cells to cease dividing and to support germ cell development. Microarray analysis of P20 Cldn11 +/- and Cldn11-/- testes confirmed the impact od Cldn11 deficiency on cell cytoskeleton and junction-related genes. Keywords: transcriptomic analysis Two-condition experiment: P20 Cldn11 +/- vs. P20 Cldn11 -/- testes. A pool of RNA from P20 Cldn11 +/- group was used as the reference group. Each P20 Cldn11 -/- was compared to reference group. Three biological replicates were processed in dye swap.
实验种类:: transcription profiling by array
样本量:: 12
实验设计:
: 无设计数据
数据号:: E-GEOD-15492, GSE15492
数据状态:: 无法自动分析，您可以尝试手动分析数据。

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