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题目:: Transcription profiling of human embryonic (9-12w) and post-natal livers
ID:
状态:: 发布时间Oct. 10, 2009 , 更新时间 June 10, 2011 , 提交时间 March 16, 2009,
物种:: Homo sapiens
摘要:: The liver is a multifunctional organ, which undergoes rapid changes during the developmental period and relies on tightly-regulated gene expression. Little is known regarding the complex expression patterns of mRNAs during the early stages of human liver development in comparison to post-natal livers. We used microarrays to detail the global programme of gene expression during liver development following specification, at the stage of proliferation and differentiation when compared to post-natal livers, and identified distinct classes of up-regulated and downregulated genes during this process. Experiment Overall Design: Liver tissues of aborted human embryos (9-12 weeks from last period) and adult patients (1.5, 42 and 81 years) were obtained under an IRB approval for RNA extraction and hybridization on Affymetrix microarrays. RNA extracted from tissues of a whole embryo without the liver tissue served as a control.
实验种类:: transcription profiling by array
样本量:: 13
实验设计:
: 无设计数据
数据号:: E-GEOD-15238, GSE15238
数据状态:: 无法自动分析，您可以尝试手动分析数据。

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