Transcriptome analysis of in vitro endotoxin tolerant human monocytes
ID:
状态:
发布时间March 13, 2009
, 更新时间 June 10, 2011
, 提交时间 March 13, 2009,
物种:
Homo sapiens
摘要:
Monocyte exposure to lipopolysaccharide (LPS) induces a transient state in which these cells are refractory to further endotoxin stimulation. Here we demonstrate the transcriptome analysis of in vitro generated LPS refractory monocytes upon subsequent re-exposure to LPS for different time points. Total RNA obtained from human monocyte exposure treated with LPS for 3h, 6h, or 24h, subsequent to endotoxin tolerization or not.