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题目:: Gene expression profiling in Daphnia magna, Part III: Uncovering Biomarkers for Metal and ORC exposures
ID:
状态:: 发布时间May 18, 2010 , 更新时间 May 4, 2014 , 提交时间 Oct. 12, 2008,
物种:: Daphnia magna
摘要:: To determine toxicant specific effects of Ordnance Related Compound (ORC) exposure we performed microarray hybridizations with RNA isolated from Daphnia magna following different ORC exposures at the 1/10 LC50. The gene expression profiles revealed toxicant specific gene expression profiles allowed for the identification of specific biomarkers of exposure. Keywords: ecotoxicogenomic exposure study We exposed Daphnia magna the 1/10 LC50 of different Ordnance Related Compounds (Cu, Zn, Pb, WO4, RDX, TNT, 2-ADNT, 2-ADNT, TNB, DNB, 2,4-DNT, and 2,6-DNT) for 24 hours. For each exposure condition, we performed 3 exposures and 2 technical replicates (as dye swap) for each exposure (6 microarrays total, except TNT and Cu). All exposures were compared to a unexposed laboratory control (MHRW media).
实验种类:: transcription profiling by array
样本量:: 140
实验设计:
: 无设计数据
数据号:: E-GEOD-13169, GSE13169
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