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题目:: RNAi profiling of mouse macrophage response to DAP12 knockdown in basal conditions and in the response to IL-4 Basal and IL-4 response in DAP12 (TYROBP) KO mice
ID:
状态:: 发布时间Oct. 26, 2008 , 更新时间 June 10, 2011 , 提交时间 Oct. 9, 2008,
物种:: Mus musculus
摘要:: DAP12 is a transmembrane protein, expressed as a disulfide-bonded homodimer and bears an immunoreceptor tyrosine-based activation motif (ITAM). DAP12 is broadly expressed in hematopoietic cells and associates with a variety of cell surface receptors in lymphoid and myeloid cells. Macrophages express several DAP12-associated receptors including triggering receptors expressed by myeloid cells (TREM)-1,2 and 3, myeloid DAP12-associating lectin (MDL)-1, CD200R like proteins CD200R3/R4 and CD300C/D/E . Experiment Overall Design: The current experiment was designed to evaluate the effect of DAP12 knockdown on macrophage gene expression, both in basal conditions and in the response to IL-4.
实验种类:: RNAi profiling by array
样本量:: 4
实验设计:
: 无设计数据
数据号:: E-GEOD-13140, GSE13140
数据状态:: 无法自动分析，您可以尝试手动分析数据。

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