实验库 数据相关信息

题目:
Expression data from Balb/c mice kidney samples
ID:
状态:
发布时间March 3, 2010 , 更新时间 May 1, 2014 , 提交时间 Sept. 4, 2008,
物种:
Mus musculus
摘要:
Males are 50% more likely to develop end stage kidney failure compared to women. As a model of the human condition we analyzed gene expression changes in healthy and diseased mouse kidneys. Interestingly, the set of gender biased genes in healthy kidneys were different from those in diseased kidneys indicating not only baseline gene expression differences but also that the male and female kidney respond differently to disease condition. Keywords: Gender difference We used AffymetrixM430A2.0 microarrays to determine global gene expression differences in kidneys of 10-week old healthy Balb/c male and female mice. In order to identify gene expression differences under disease conditions, animals were injected with doxorubicin, a substance that is known to induce albuminuria and glomerulosclerosis in Balb/c mice as it is directly toxic to podocytes.
实验种类:
transcription profiling by array
样本量:
20
实验设计:
无设计数据
数据号:
E-GEOD-12683, GSE12683
数据状态:

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