Transcription profiling of mouse AC61 cells were derived from a C-cell adenocarcinoma developed in Rb+/-N-ras-/- mouse transfected with pRb to identify genes that are regulated by pRb in AC61 cells
This experiment is to identify genes that are regulated by pRb in AC61 cells. AC61 cells were derived from a C-cell adenocarcinoma developed in an Rb+/-N-ras-/- mouse. Experiment Overall Design: AC61 cells were infected with retrovirus derived from pLXSB or pLSXB-Rb and selected with balsticidin for 36 hours. At 72 hour after infection, cells were quickly frozen.