Transcription profile of an azole resistant mutant of Mycobacterium truberculosis
ID:
状态:
发布时间July 31, 2008
, 更新时间 May 3, 2014
, 提交时间 July 29, 2008,
物种:
Mycobacterium tuberculosis
摘要:
We used DNA microarrays to detect differentially expresses genes in a spontaneous mutant of Mycobacterium tuberculosis H37Rv resistant to azoles. We identified three adjacent upregulated genes encoding a transcription regulatory protein and two membrane proteins belonging to the family of RND efflux transporters. Hybridization were performed using RNA extracted from three different biological samples coming from cultures grown in mid-exponential phase.