Transcription profiling of human dendritic cells treated with Echinacea purpurea phytocompounds
ID:
状态:
发布时间Oct. 25, 2008
, 更新时间 May 3, 2014
, 提交时间 July 28, 2008,
物种:
Homo sapiens
摘要:
This study investigated the specific and differential gene expression in human immature DCs (iDCs) in response to treatment with a butanol fraction containing defined bioactive phytocompounds extracted from stems and leaves of Echinacea purpurea Experiment Overall Design: Human immature DCs (iDCs) differentiated from primary monocytes in vitro were incubated with [BF/S+L/Ep] or cichoric acid for 4 or 24 h to characterize early- or late-responsive genes. A total of nine Affymetrix HU-133A chips were hybridized to determine the transcriptome profiles in human iDCs.