Transcription profiling of human primary keratinocytes treated with either IL-17, IL-22 or IFNg
ID:
状态:
发布时间Oct. 24, 2008
, 更新时间 June 10, 2011
, 提交时间 July 14, 2008,
物种:
Homo sapiens
摘要:
In this study, we shought to identify the cytokines produced by skin-resident T cells in normal skin, localize the receptors for these cytokines, and examine how these cytokines alter gene expression profiles of the cells bearing cognate receptors. Experiment Overall Design: In this study, primary keratinocytes were treated with either IL-17, IL-22 or IFNg for 24 hours then harvested for RNA extraction and subsequent gene array analysis